Antidote for nondepolarizing neuromuscular blocker-
Neonate, infant: 0.04 mg/kg IV
with 0.02 mg/kg atropine.
Adult: 0.5-2 mg slow IV. Repeat prn. Max total dose, 5 mg. Give 0.6-1.2 mg atropine sulfate
IV before antidote dose if pt bradycardic.
Myasthenia gravis-
Neonate: 0.1-0.2 mg SC or 0.03 mg/kg IM q 2-4 h, or 1-4 mg PO q
2-3 h. Gradually reduce dose untill drug can be discontined.
Child: 7.5-15 mg PO tid-qid. Or 0.333 mg/kg IM or 10 mg/m2 PO 6 times qd.
Adult: 0.5 mg SC or IM. Or 15-375 mg/day PO. |